Three people were injured, including a woman whose arm was amputated, in a crash early Sunday on the Eisenhower Expressway on the Near West Side.

A man was driving a black Chevrolet Impala east on I-290 at 4:35 a.m. when he lost control of the car near Racine Avenue and veered off the right shoulder into a grassy embankment, according to Illinois State Police.

Two women, ages 27 and 38, were riding in the car, police said. One of the women suffered non-life-threatening injuries and the other suffered a major injury to her right arm, which had to be amputated.

The driver and both women were taken to Stroger Hospital, police said.

The investigation into the crash is ongoing.