The Sox probably wished Saturday that they had saved some of their nine runs from Friday for another day.

The team struggled offensively, watching its first nine batters fail to reach base for the second consecutive game in a 4-3 loss to the Arizona Diamondbacks at U.S. Cellular Field.

The Diamondbacks struck first with a three-run fifth inning courtesy of Alfredo Marte’s two-run double and A.J. Pollock’s RBI single that drove in Marte.

The Sox responded in the bottom half. Paul Konerko — who started at first base in place of Adam Dunn, who was given the day off —hit a two-run homer that scored Dayan Viciedo. The homer was the 435th of Konerko’s career and moved him past Andruw Jones and Juan Gonzalez into sole possession of 43rd place on the all-time list.

Sox starter Jose Quintana gave up three runs and seven hits and struck out five in six innings.

The Diamondbacks scored an insurance run in the seventh after Sox reliever Zach Putnam pitched himself into a one-out, bases-loaded jam. The inning ended when Putnam induced a double-play grounder.

Daniel Webb pitched a scoreless eighth and ninth.

Sox pinch hitter Conor Gillaspie lead off the ninth with a single and was driven in by Alexei Ramirez with two outs. But Diamondbacks closer Addison Reed, whom the Sox traded to the D-backs in December, got Konerko to ground out to second.

Email: sgruen@suntimes.com

Twitter: @SethGruen