KANSAS CITY, Mo. — Adam Dunn hit a three-run homer to break open a tight game, Tyler Flowers also homered and Andre Rienzo pitched six strong innings as the White Sox defeated the Kansas City Royals 7-6 on Tuesday night.

Dunn’s seventh homer, a 426-foot shot to center against reliever Aaron Crow in the eighth inning, gave the Sox a 7-2 lead. The Royals (22-23) scored three in the eighth against relievers Scott Downs and Frank Francisco to get within two, but Ronald Belisario got his first save despite giving up a run in the ninth as the Sox (23-24) took the first two games of the series.

The Sox will go for the sweep when they close a nine-game road trip Thursday night.

Before the game, the Sox put closer Matt Lindstrom on the 15-day disabled list with a sublexing outside tendon in his left ankle. Manager Robin Ventura and pitching coach Don Cooper did not say who the new closer would be, but they turned to Belisario, who went into the game with seven consecutive scoreless relief appearances. Belisario retired the first two Royals in the ninth before Billy Butler doubled and Alex Gordon drove him in with a single. Pinch runner Jarrod Dyson stole second before Belisario struck out Lorenzo Cain to end the game.

Rienzo (4-0, 4.00 ERA) gave up two runs, five hits and two walks while striking out eight as the Sox improved to 6-0 in his starts.

Flowers hit his third home run, a 412-foot shot inside the left-field foul pole, for the first of three Sox runs in the fifth. A double by Adam Eaton, a wild pitch by Royals starter Yordano Ventura (2-4), an RBI single by Gordon Beckham (3-for-5) and two more wild pitches by Ventura helped the Sox get two more runs for a 4-2 lead.

In the first, Conor Gillaspie (3-for-4) tripled to right with two outs, and Dayan Viciedo singled. The Royals scored two against Rienzo in the second on Danny Valencia’s two-run double.

Zach Putnam entered in the eighth to clean up after Francisco, retiring pinch hitter Mike Moustakas and Nori Aoki with runners at first and third. The Royals scored two in the eighth against Downs and one against Franciso, who faced three batters but did not record an out.