The Cubs scored five runs in the second, and it was up to Steve Cishek, Brandon Kintzler and Pedro Strop to hold a one-run lead from the sixth on.
Darvish said his recovery turned a corner when treatment shifted to his spine and back.
By the end of the night, nearly all 29,442 in attendance were on their feet, making noise and enjoying a win like few others this season.
Matt Davidson told reporters he’d “love to explore” the idea of pitching more often. Rick Renteria shot that idea down Saturday.
Rizzo reached base safely in eight of his 10 plate appearances. He went 4-for-5 with an RBI in the 6-3 loss in Game 2.
His trade to the Cubs on Thursday marked the fourth time in his 11-year career that he has been part of a midseason trade.
Shields pitched seven-plus innings and allowed three runs — all on solo homers — in the Sox’ 5-0 loss Saturday to the Brewers.
“Not playing Caratini enough really bums me out,” Joe Maddon said. “It bothers me a lot. And he needs to play. We got to get him out playing again.”
Darvish was scheduled to start Sunday night against the Giants at Wrigley Field. Tyler Chatwood will take his place.
‘‘You always look at the quality of the bench, and our bench is outstanding,’’ Maddon said. ‘‘So that tells you how good the team is.’’
Bryant, who received an ovation from fans before his first at-bat, went 0-for-3 with a walk but said he felt good. Zobrist singled and scored a run.
Moncada said he felt tightness in his left hamstring on a grounder in the second inning. Giolito allowed nine earned runs in two-plus innings.
Farquhar, 31, is in critical but stable condition at Rush. Overnight testing revealed a ruptured aneurysm caused the bleeding in the brain.
Efren Navarro grew up in Southern California emulating J.T. Snow and Cubs All-Star Mark Grace, both left-handed first basemen like himself.