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Why do we get hangovers?

The telltale signs you had a little too much to drink last night: headaches, nausea, trembling and body aches. We all know them, but why do we get them?

And why do some of us have much worse hangovers than others?

Discovery Channel’s TestTube Video can explain the mechanism (as much as is known) of a hangover, and why some people just don’t get them at all.