The closures are required for a traffic signal modernization project along Route 120 and U.S. 45, IDOT said.
Lanes on the Interstate-90/94 bridge over the Chinatown Feeder will close this weekend near the South Side Bridgeport neighborhood.
Road resurfacing will close lanes on Route 31 in northwest suburban Crystal Lake.
The inspection of a railroad bridge that crosses Cicero Avenue will close lanes Saturday near Cicero in the west suburbs.
Lanes on the Reagan Memorial Tollway will temporarily close during the removal of two bridges in west suburban Dixon.
Lanes were closed Monday for construction on the Roselle Road Interchange on the Jane Addams Memorial Tollway in northwest suburban Schaumburg.
Drivers can expect delays on Saturday on the Kennedy Expressway due to lane closures for pavement repairs on the North Side.
Several closures are scheduled for overnight Friday on the Stevenson Expressway and Lake Shore Drive.
A brand-new section of Elston has opened near the intersection of the avenue with Damen and Fullerton in Bucktown, the city announced Tuesday.
Lane and ramp closures on I-290 and Illinois Route 390 are scheduled to begin Monday to replace bridge beams.
Lane closures will begin Tuesday for resurfacing on Roosevelt Road in the Lawndale neighborhood on the West Side.
Lane closures began Monday in the Far South Side Mount Greenwood neighborhood and south suburban Merrionette Park, Alsip, Blue Island and Robins.
Lane closures on West Belmont in the North Side Roscoe Village neighborhood began Monday for sewer reconstruction.