Protesters were arrested as they walked on the Dan Ryan Expressway and blocked traffic Thursday afternoon.
Troopers responded after several pedestrians and cars were reported blocking traffic on the southbound lanes near Garfield Boulevard, Illinois State Police said.
Troopers cleared the cars and pedestrians and took some protesters into custody, state police said.
Details on how many arrests were made were not immediately available. All southbound lanes were reopened about 4 p.m., state police said.